Installation of biomodal duet software

Cluster Help requests
1

Bonjour,

My lab is using biomodal’s duet multiomics evoC assay to perform DNA sequencing of modified cytosines (duet multiomics solution evoC | biomodal).
Due to the nature of the assay, the company provides their own software for data processing (biomodal duet software installation and running: Quick Start Guide — biomodal CLI 2.0.0 documentation)

I would like to know if it’s possible to install the duet software in the iPOP-UP cluster. Their technical support has offered guidance should we encounter any difficulties.

A user authentication step is required as part of the setup; I’m happy to provide my credentials through a private channel.

Thanks in advance!
Marlet

2

Hello Marlet,

You can perform the installation yourself directly within your project space, without requiring administrator privileges.

The biomodal CLI is designed to run as a standalone binary, and it packages its own nextflow orchestrator and containerized dependencies. Since our cluster already has apptainer installed globally, you have everything you need to proceed autonomously.

Please use your project directory (/shared/projects/methylenh) when setting the BIOMODAL_INSTANCE_DIRECTORY and not your home directory.

Something like this:

export BIOMODAL_INSTANCE_DIRECTORY=/shared/projects/methylenh/.biomodal

Then download the installation script and run:

biomodal init

(I believe) This is the step where the software will prompt you for your credentials to securely download the nextflow pipeline and its configuration.

Best,